> Dr. Σ. ΔΕΡΚΑ  > ΕΡΕΥΝΗΤΙΚΟ ΕΡΓΟ

Α. ΕΠΙΣΤΗΜΟΝΙΚΕΣ ΔΙΑΚΡΙΣΕΙΣ

 

Η Dr. Σπυριδούλα Δέρκα έλαβε το 2007, το 1ο βραβείο Βασικής Έρευνας στο Παγκόσμιο Συνέδριο Ογκολογίας Στόματος στο Άμστερνταμ για ένα μεγάλο μέρος του ερευνητικού της έργου, που εστιάζεται κυρίως στον Καρκίνο του Στόματος.

 

 

Β. ΔΗΜΟΣΙΕΥΣΕΙΣ ΣΕ ΔΙΕΘΝΗ ΕΠΙΣΤΗΜΟΝΙΚΑ ΠΕΡΙΟΔΙΚΑ

 

Ένας μεγάλος αριθμός μελετών της Dr. Σπυριδούλα Δέρκα έχει δημοσιευθεί σε διεθνή επιστημονικά περιοδικά. Οι μελέτες αυτές είναι οι εξής:

 

1. Derka S, Vairaktaris E, Papakosta V, Vassiliou S, Acil Y, Vylliotis A, Spyridonidou S, Lazaris AC, Mourouzis C, Kokkori A, Moulavasili P, Perrea D, Donta I, Yapijakis C, Patsouris E. Cell proliferation and apoptosis culminate in early stages of oral oncogenesis. Oral Oncol. 2006 May;42(5):540-50.

 

2. Yapijakis C, Serefoglou Z, Vylliotis A, Nkenke E, Derka S, Vassiliou S, Avgoustidis D, Neukam FW, Patsouris E, Vairaktaris E. Association of polymorphisms in Tumor Necrosis Factor Alpha and Beta genes with increased risk for oral cancer. Anticancer Res. 2009 Jun;29(6):2379-86.

 

3. Vairaktaris E, Papakosta V, Derka S, Vassiliou S, Nkenke E, Spyridonidou S, Vylliotis A, Lazaris A, Kokkori A, Moulavassili P, Loukeri S, Perrea D, Donta I,Yapijakis C, Patsouris E. H-ras and c-fos exhibit similar expression patterns during most stages of oral oncogenesis. In Vivo. 2008 Sep-Oct;22(5):621-8.

 

4. Vairaktaris E, Serefoglou Z, Avgoustidis D, Yapijakis C, Critselis E, Vylliotis A, Spyridonidou S, Derka S, Vassiliou S, Nkenke E, Patsouris E. Gene polymorphisms related to angiogenesis, inflammation and thrombosis that influence risk for oral cancer. Oral Oncol. 2009 Mar;45(3):247-53.

 

5. Vairaktaris E, Yapijakis C, Vylliotis A, Derka S, Vassiliou S, Nkenke E, Serefoglou Z, Ragos V, Critselis E, Avgoustidis D, Neukam F, Patsouris E. Angiotensinogen polymorphism is associated with risk for malignancy but not for oral cancer. Anticancer Res. 2008 May-Jun;28(3A):1675-9.

 

6. Vairaktaris E, Yapijakis C, Serefoglou Z, Derka S, Vassiliou S, Nkenke E, Vylliotis A, Spyridonidou S, Neukam FW, Schlegel KA, Patsouris E. The interleukin-10 (-1082A/G) polymorphism is strongly associated with increased risk for oral squamous cell carcinoma. Anticancer Res. 2008 Jan-Feb;28(1A):309-14.

 

7. Vairaktaris E, Vylliotis A, Spyridonodou S, Derka S, Vassiliou S, Nkenke E, Yapijakis C, Serefoglou Z, Neukam FW, Patsouris E. A DNA polymorphism of stromal-derived factor-1 is associated with advanced stages of oral cancer. Anticancer Res. 2008 Jan-Feb;28(1A):271-5.

 

8.  Vairaktaris E, Yapijakis C, Serefoglou Z, Avgoustidis D, Critselis E, Spyridonidou S, Vylliotis A, Derka S, Vassiliou S, Nkenke E, Patsouris E. Gene expression polymorphisms of interleukins-1 beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma. J Cancer Res Clin Oncol. 2008 Aug;134(8):821-32.

 

9. Vairaktaris E, Yapijakis C, Vasiliou S, Derka S, Nkenke E, Serefoglou Z, Vorris E, Vylliotis A, Ragos V, Neukam FW, Patsouris E. Association of -1171 promoter polymorphism of matrix metalloproteinase-3 with increased risk for oral cancer. Anticancer Res. 2007 Nov-Dec;27(6B):4095-100.

 

10. Vairaktaris E, Yapijakis C, Nkenke E, Serefoglou ZC, Chatzitheofylaktou A, Vassiliou S, Derka S, Vylliotis A, Perrea D, Neukam FW, Patsouris E. A metalloproteinase-13 polymorphism affecting its gene expression is associated with advanced stages of oral cancer. Anticancer Res. 2007 Nov-Dec;27(6B):4027-30.

 

11. Vairaktaris E, Serefoglou Z, Yapijakis C, Stathopoulos P, Vassiliou S, Derka S, Nkenke E, Vylliotis A, Ragos V, Neukam FW, Patsouris E. The interleukin-1 beta gene polymorphism +3953 C/T is not associated with risk for oral cancer. Anticancer Res. 2007 Nov-Dec;27(6B):3981-6.

 

12. Vassiliou S, Yapijakis C, Derka S, Papakosta V, Psyrri A, Antonakis P, Goutzanis L, Konstadoulakis M, Androulakis G, Vairaktaris E. Evaluation of apoptosis in nasal and buccal cells of septic patients. In Vivo. 2007 Sep-Oct;21(5):901-4.

 

13.  Vairaktaris E, Goutzanis L, Nkenke E, Spyridonidou S, Vassiliou S, Derka S, Vylliotis A, Yapijakis C, Lazaris A, Patsouris E. Expression of cell cycle regulator p16 is not affected by diabetes during oral oncogenesis. In Vivo. 2007 Sep-Oct;21(5):745-50.

 

14. Vairaktaris E, Vassiliou S, Yapijakis C, Spyridonidou S, Vylliotis A, Derka S, Nkenke E, Fourtounis G, Neukam FW, Patsouris E. Increased risk for oral cancer is associated with coagulation factor XIII but not with factor XII. Oncol Rep. 2007 Dec;18(6):1537-43.

 

15. Vairaktaris E, Yapijakis C, Tsigris C, Vassiliou S, Derka S, Nkenke E, Spyridonidou S, Vylliotis A, Vorris E, Ragos V, Neukam FW, Patsouris E. Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with increased risk for oral cancer. Acta Oncol. 2007;46(8):1097-102.

 

16. Vairaktaris E, Kalokerinos G, Goutzanis L, Yapijakis C, Derka S, Vassiliou S, Spyridonidou S, Vylliotis A, Nkenke E, Lazaris A, Patsouris E. Diabetes enhances cell proliferation but not Bax/Bcl-2-mediated apoptosis during oral oncogenesis. Int J Oral Maxillofac Surg. 2008 Jan;37(1):60-5.

 

17. Vairaktaris E, Goutzanis L, Nkenke E, Spyridonidou S, Vassiliou S, Derka S, Vylliotis A, Yapijakis C, Lazaris A, Strantzias P, Kalimeras E, Patsouris E. Diabetes does not influence oral oncogenesis through fibroblast growth factor receptors. In Vivo. 2007 Jul-Aug;21(4):623-8.

 

18. Vairaktaris E, Serefoglou Z, Yapijakis C, Vylliotis A, Nkenke E, Derka S, Vassiliou S, Avgoustidis D, Neukam FW, Patsouris E. High gene expression of matrix metalloproteinase-7 is associated with early stages of oral cancer.  Anticancer Res. 2007 Jul-Aug;27(4B):2493-8.

 

19. Vairaktaris E, Yapijakis C, Nkenke E, Vassiliou S, Vylliotis A, Nixon AM, Derka S, Ragos V, Spyridonidou S, Tsigris C, Neukam FW, Patsouris E. The 1040C/T polymorphism influencing thermal stability and activity of thrombin activatable fibrinolysis inhibitor is associated with risk for oral cancer.  Am J Hematol. 2007 Nov;82(11):1010-2.

 

20. Vairaktaris E, Kalokerinos G, Goutzanis L, Spyridonidou S, Vassiliou S, Derka S, Nkenke E, Yapijakis C, Vylliotis A, Lazaris A, Patsouris E. Diabetes alters expression of p53 and c-myc in different stages of oral oncogenesis. Anticancer Res. 2007 May-Jun;27(3B):1465-73.

 

21. Yapijakis C, Vairaktaris E, Vassiliou S, Vylliotis A, Nkenke E, Nixon AM, Derka S, Spyridonidou S, Vorris E, Neukam F, Patsouris E. The low VEGF production allele of the +936C/T polymorphism is strongly associated with increased risk for oral cancer. J Cancer Res Clin Oncol. 2007 Oct;133(10):787-91.

 

22. Vairaktaris E, Vassiliou S, Nkenke E, Serefoglou Z, Derka S, Tsigris C, Vylliotis A, Yapijakis C, Neukam FW, Patsouris E. A metalloproteinase-9 polymorphism which affects its expression is associated with increased risk for oral squamous cell carcinoma. Eur J Surg Oncol. 2008 Apr;34(4):450-5.

 

23. Vairaktaris E, Yapijakis C, Derka S, Serefoglou Z, Vassiliou S, Nkenke E, Ragos V, Vylliotis A, Spyridonidou S, Tsigris C, Yannopoulos A, Tesseromatis C, Neukam FW, Patsouris E. Association of matrix metalloproteinase-1 (-1607 1G/2G) polymorphism with increased risk for oral squamous cell carcinoma. Anticancer Res. 2007 Jan-Feb;27(1A):459-64.

 

24. Vairaktaris E, Yapijakis C, Yiannopoulos A, Vassiliou S, Serefoglou Z, Vylliotis A, Nkenke E, Derka S, Critselis E, Avgoustidis D, Neukam FW, Patsouris E. Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans. Oncol Rep. 2007 Apr;17(4):963-8.

 

25. Vairaktaris E, Ragos V, Yapijakis C, Derka S, Vassiliou S, Nkenke E, Yannopoulos A, Spyridonidou S, Vylliotis A, Papakosta V, Loukeri S, Lazaris A, Tesseromatis C, Tsigris C, Patsouris E. FGFR-2 and -3 play an important role in initial stages of oral oncogenesis. Anticancer Res. 2006 Nov-Dec;26(6B):4217-21.

 

26. Vairaktaris E, Yiannopoulos A, Vylliotis A, Yapijakis C, Derka S, Vassiliou S, Nkenke E, Serefoglou Z, Ragos V, Tsigris C, Vorris E, Critselis E, Avgoustidis D, Neukam FW, Patsouris E. Strong association of interleukin-6 -174 G>C promoter polymorphism with increased risk of oral cancer. Int J Biol Markers. 2006 Oct-Dec;21(4):246-50.

 

27. Vairaktaris E, Yapijakis C, Serefoglou Z, Derka S, Vassiliou S, Nkenke E, Vylliotis A, Wiltfang J, Avgoustidis D, Critselis E, Neukam FW, Patsouris E. The interleukin-8 (-251A/T) polymorphism is associated with increased risk for oral squamous cell carcinoma. Eur J Surg Oncol. 2007 May;33(4):504-7.

 

28. Vairaktaris E, Papageorgiou G, Derka S, Moulavassili P, Nkenke E, Kessler P, Vassiliou S, Papakosta V, Spyridonidou S, Vylliotis A, Lazaris AC, Anagnostopoulou S, Mourouzis C, Yapijakis C, Patsouris E. Expression of ets-1 is not affected by N-ras or H-ras during oral oncogenesis. J Cancer Res Clin Oncol. 2007 Apr;133(4):227-33.

 

29. Papakosta V, Vairaktaris E, Vylliotis A, Derka S, Nkenke E, Vassiliou S, Lazaris A, Mourouzis C, Rallis G, Spyridonidou S, Anagnostopoulou S, Perrea D, Donta I, Yapijakis C, Patsouris E. The co-expression of c-myc and p53 increases and reaches a plateau early in oral oncogenesis. Anticancer Res. 2006 Jul-Aug;26(4B):2957-62.

 

30. Goutzanis L, Vairaktaris E, Yapijakis C, Kavantzas N, Nkenke E, Derka S,Vassiliou S, Acil Y, Kessler P, Stavrianeas N, Perrea D, Donta I, Skandalakis P, Patsouris E. Diabetes may increase risk for oral cancer through the insulin receptor substrate-1 and focal adhesion kinase pathway. Oral Oncol. 2007 Feb;43(2):165-73.

 

31. Vairaktaris E, Yapijakis C, Serefoglou Z, Vylliotis A, Ries J, Nkenke E, Wiltfang J, Derka S, Vassiliou S, Springer I, Kessler P, Neukam FW. Plasminogen activator inhibitor-1 polymorphism is associated with increased risk for oral cancer. Oral Oncol. 2006 Oct;42(9):888-92.

 

32. Vairaktaris E, Yapijakis C, Derka S, Vassiliou S, Serefoglou Z, Vylliotis A, Wiltfang J, Springer I, Nkenke E, Kessler P, Neukam FW. Association of platelet glycoprotein Ia polymorphism with minor increase of risk for oral cancer. Eur J Surg Oncol. 2006 May;32(4):455-7.

 

33. Vairaktaris E, Yapijakis C, Kessler P, Vylliotis A, Ries J, Wiltfang J, Vassiliou S, Derka S, Neukam FW. Methylenetetrahydrofolate reductase polymorphism and minor increase of risk for oral cancer. J Cancer Res Clin Oncol. 2006 Apr;132(4):219-22.

 

34. Vairaktaris E, Yapijakis C, Wiltfang J, Ries J, Vylliotis A, Derka S, Vasiliou S, Neukam FW. Are factor V and prothrombin mutations associated with increased risk of oral cancer? Anticancer Res. 2005 May-Jun;25(3c):2561-5.

 

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